Nexderma Hypoallergenic — Hero Section
🐾 New — Hypoallergenic Formula
★★★★★ 4.9 stars from 180+ store reviews  |  62,000+ units sold

For dogs with extra, extra
sensitive skin.

The same nano colloidal silver formula — now hypoallergenic. Zero harsh ingredients. Free from sulfates, parabens, dyes, alcohol, and more. Built for pets who react to everything.

Shop Hypoallergenic Shampoo
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Veterinarian Recommended
Nexderma Hypoallergenic Shampoo
Nexderma Hypo — Proof Bar
Clinically Studied
Vet Recommended
No Harsh Ingredients
Nexderma Hypo — With/Without Section

Hypoallergenic Formula

Everything they need.
Nothing they don't.

Made for dogs with extra, extra sensitive skin — the full benefit of nano colloidal silver, without a single ingredient that could set them back.

What's in it
What's not in it
Nexderma Hypoallergenic Shampoo
Nano Colloidal Silver
Attacks yeast, bacteria, and fungi through four pathways at once — soothes irritation and stops the cycle from the very first wash.
Aloe Vera + Jojoba Oil
Aloe calms redness on contact. Jojoba mimics the skin's natural sebum to rebalance oil production and keep the barrier intact.
Glycerin + Olive Oil
Glycerin locks moisture in between washes. Olive oil softens the coat and repairs the skin from the outside in.
No Sulfates or Soap
Cleans thoroughly without stripping the skin barrier. Sulfates are one of the fastest ways to dry out sensitive skin — we don't touch them.
No Fragrance, Dyes, or Alcohol
Fragrance is the #1 trigger for skin reactions in sensitive dogs. Zero artificial scents, zero dyes, zero alcohol. Won't sting. Safe to lick.
No Parabens, Phosphates, or Phthalates
None of the filler chemicals found in most pet shampoos. Just what works — nothing your dog has to process, absorb, or react to.

2 WEEK DIFFERENCE

Using Nexderma Silvet Shampoo With Hydrocortisone

Before After
The Yeast Cycle — Nexderma

Why Yeast Is So Difficult to Treat

Traditional treatments kill yeast. But the treatment itself can trigger the next infection. It's a $20 billion industry built on a cycle that never ends — and your dog pays the price every year.

The yeast cycle — why it keeps coming back
Social Proof — Nexderma
Real Results

Trusted by vets, groomers, & pet owners

Over 62,000 products sold. 5,000+ groomers and veterinarians reach for Silvet.

Dr. Amanda Vyvian Gorbea Verified DVM
★★★★★

My dog Kodi has horrible skin dermatitis. Since we started using the shampoo, his skin has cleared up significantly!

Dr. Amanda Vyvian Gorbea D.V.M., Ph.D

Verified Veterinarian · Nexderma Clinical Partner

What pet owners & groomers are saying

★★★★★

"We love it! All my groomers are very happy with the change and we see very beneficial results on the dog's skin. The yeast issues we were dealing with have cleared up noticeably."

K

Keky

Verified buyer · Professional Grooming Business Owner

★★★★★

"I used it on a very itchy dog I groom — the next day my client messaged asking what I used. Her dog hadn't itched since the appointment. I am definitely a believer."

M

Marcie

Owner, Heaven Scent Grooming

★★★★★

"I've been grooming for 20+ years and am allergic to chlorhexidine. Love having another option — this shampoo leaves both groomer and dog's skin feeling amazing."

S

Stacie Scott

Professional Groomer · 20+ years

Dr. Mara Di Grazzia

"If the dogs have very inflammed skin I will use the silvet with TA and I have seen changes immediately within 1-2 uses."

Nexderma — What's Not Included

What we left out.

Every ingredient in this formula was chosen deliberately. So was everything we left out. These are the common irritants you won’t find here, and the reason each one was excluded.

✕ Not included

Sulfates (SLS/SLES)

Can strip natural skin oils and cause dryness. Hard to fully rinse from dense coats, prolonging irritation after every bath.

✕ Not included

Parabens

Readily absorbed through skin and act as endocrine disruptors. The Environmental Working Group lists them as skin toxicants and allergens.

✕ Not included

Synthetic Fragrances

The most common hidden trigger for allergic reactions in sensitive animals. Often contain dozens of undisclosed chemicals under a single label.

✕ Not included

Phthalates

Frequently concealed under "fragrance" on labels. Hormone disruptors associated with reproductive issues and skin irritation with repeated exposure.

✕ Not included

Phosphates

Harsh cleaning agents that strip the skin's protective acid mantle, leaving it immediately vulnerable to bacterial and yeast colonisation after bathing.

✕ Not included

DEA

Diethanolamine is a potential carcinogen commonly used as a foaming agent. Completely excluded from every Nexderma formula.

✕ Not included

Synthetic Dyes

Offer zero skincare benefit and are a known trigger for reactions in pets with sensitivities. The formula's colour comes only from its natural ingredients.

✕ Not included

Soap

Traditional soap disrupts the skin's pH and strips the protective lipid layer. Soap-free cleansing is gentler and rinses more completely from the coat.

The Science — Nexderma
Peer-Reviewed Clinical Data

This isn't marketing — it's science.

A 2023 pilot study published in the Journal of the American Animal Hospital Association tested Silvet's exact formulation on dogs with confirmed Malassezia dermatitis. The results speak for themselves.

Journal of the American Animal Hospital Association · 2023 Pilot Study

Silver nanoparticles offer a clinically proven alternative to traditional antifungals

14 dogs with confirmed Malassezia dermatitis were bathed with Silvet's 30ppm nano-silver shampoo every 48 hours for 28 days. Result: a highly effective, non-azole, non-antibiotic solution with zero adverse effects reported.

Authors: Jones, S. & Bloom, P.
Institution: Michigan State University, Veterinary Dermatology Program
Published: Journal of the American Animal Hospital Association, 2023

Read the full study on PubMed
79%

of dogs achieved complete cytological clearance of Malassezia by day 28

Day 28 — Full clearance 79%
Day 14 — Already clear 64.3%

11 out of 14 dogs fully cleared by day 28. 9 out of 14 were already clear by day 14. Zero adverse reactions reported.

Four Mechanisms — Nexderma
But how does it actually kill yeast?

Four mechanisms. Zero resistance. Zero dryness.

The 4-way nano-silver attack

1
No Known Resistances
Nano silver attacks through multiple pathways simultaneously, making resistance virtually impossible.
2
Zero Dryness
The pH-balanced formula treats the infection while nourishing the skin, without the dryness and irritation chlorhexidine causes.
3
Anti-Inflammatory Action
Targets the microbial root cause of inflammation, breaking the scratch-damage-infect cycle that keeps skin conditions recurring.
4
Goes Where Others Can't
Nano silver's particle size penetrates the protective barriers that shield yeast colonies from conventional treatments.
FAQ & Guarantee — Nexderma
30 Day
Guarantee

We started Nexderma because we love animals.

That's why every order comes with our full purchase guarantee. If your pet doesn't see real improvement, we don't want your money. Contact us within 30 days for a full refund — no hoops, no fine print, no hassle. Simple as that.

Shop Risk-Free →

Free shipping over $100

FAQ

Got questions?

Everything you need to know about Silvet, how to use it, and what to expect. Still not sure? Reach out directly.

Our team is happy to help with product questions, wholesale inquiries, or veterinary support.

info@nexderma.com

(877) 215-8201
How often should I bathe my dog with Silvet?

During an active yeast flare-up, bathe every 48 hours. Once the infection clears, weekly maintenance baths help prevent recurrence. Always allow 5–10 minutes of contact time before rinsing for best results.

Is nano-silver safe for my dog?

Yes. The 30ppm concentration in Silvet is completely safe — no stinging, no skin discoloration, and no adverse systemic absorption. It selectively targets microbial cells without damaging your pet's tissue, and is safe to use around eyes, nose, and mouth.

Why is Silvet better than chlorhexidine or ketoconazole shampoos?

Traditional antifungals work through a single mechanism, which yeast can develop resistance to over time — that's why infections keep coming back. Silvet's nano-silver attacks through four simultaneous mechanisms, making resistance virtually impossible. It also contains no harsh chemicals and won't cause dryness or irritation.

Which Silvet product should I start with?

Start with the Silvet Antifungal Shampoo — it's the foundation of the protocol. If your dog has intense scratching or inflamed skin, the Triple Action + Hydrocortisone version will break the itch-scratch cycle faster. Add the Wipes for between-bath maintenance on paws and folds.

Can I use Silvet on cats and horses too?

Yes. Nexderma's Silvet line is formulated for use on dogs, cats, and horses. The formula is gentle enough for all species and all coat types.

How long before I see results?

Nano colloidal silver begins working within minutes and continues protecting for up to 24 hours, eliminating 99.999% of harmful bacteria. Most people report visible improvements — less scratching, reduced redness, better smell — within 48 hours. Consistency with the 48-hour bathing schedule and 5–10 minute contact time is key.

Do you offer wholesale pricing for groomers and vets?

Absolutely. Nexderma has a dedicated business account program for groomers, veterinarians, and equestrian professionals. Sign up for wholesale pricing, a tailored catalog, and professional support at nexderma.com/pages/business-account. It's free to join and access is instant.